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Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Dynorphin: Suffering and circumstantial theories

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

ADHD: Methylphenidate(AKA Ritalin, Concerta) causes permanent downregulation of the GABAminergic system in those treated with the drug under 16. 2017 Study.

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

what do you think?

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

what do you think?

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The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Food Restriction Increases Dopamine Receptors -- Linked to Pleasure -- In Rats

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Food Restriction Increases Dopamine Receptors -- Linked to Pleasure -- In Rats

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Exploring Darkness: 'Theory of Creativity' - Dopamine D2 D4 receptor links

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Tobacco Usage Causes Brain-Wide Reductions in Cannabinoid Receptors (2018)

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Tobacco Usage Causes Brain-Wide Reductions in Cannabinoid Receptors (2018)

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction - PubMed (2016)

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction - PubMed (2016)

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Original technique to boost growth hormone secretion during sleep + possible feedback loop - PubMed

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

ACD-856 structure analysis (google docs)

This is the FRONTLINE of nootropics where we aim to find NEW PRODUCTS for people to have on the market instead of discussing about already widely available nootropics. Research & synthesis & report discussions go here. Discussing about already widely available nootropics (racetams, theanine and etc) IS STRICTLY NOT allowed. Groupthink or enthusiasm deficiency is NOT allowed.

Ibuprofen increases BDNF levels, reverses depression caused by chronic stress exposure - PubMed (2019)

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

Ibuprofen increases BDNF levels, reverses depression caused by chronic stress exposure - PubMed (2019)

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

This is what my nootropics addiction looked like - repost

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The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

TAK-653 Reverses Core Depressive Symptoms in Chronic Stress-Induced Monkey Model - MDPI (Published Today)

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

L-Theanine Effectively Protects Against Copper-Facilitated Dopamine Oxidation: Implication for Relieving Dopamine Overflow-Associated Neurotoxicities - PubMed (Apr. 2025)

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

L-Theanine Effectively Protects Against Copper-Facilitated Dopamine Oxidation: Implication for Relieving Dopamine Overflow-Associated Neurotoxicities - PubMed (Apr. 2025)

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

(CosmicNootropic) "Lab-testing of our TOP products for COA. You Asked – We Deliver!"

The Official Subreddit of NooTopics. Where the boundaries of cognition and health are pushed by cutting edge scientific research and discussion. All biohacking science is welcome. Please note this subreddit is not for customer service.

A Paradigm Shift in Antidepressant Therapy - ACD856

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.

High-Fructose Diet Harms 940 Brain Genes, DHA could mediate damage (2016)

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, supplements, nootropics, sleep, fitness, and transhumanism. This space encourages scientific inquiry and experimentation in accessible, hands-on ways.